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Probing the physical basis for trp repressor-operator recognition

✍ Scribed by Adeola O. Grillo; Martha P. Brown; Catherine A. Royer


Book ID
115629192
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
386 KB
Volume
287
Category
Article
ISSN
0022-2836

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Flexibility of dna binding domain of trp
✍ Michael R. Gryk; Oleg Jardetzky; Lisa S. Klig; Charles Yanofsky πŸ“‚ Article πŸ“… 2008 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 279 KB

## Abstract __Trp__ repressor (25 kDa) is a regulatory protein that controls transcription initiation in the tryptophan biosynthetic operon and at least four other operons in __Escherichia coli__. An alanine to valine mutation (AV77) in the DNA binding domain is known to increase repressor activity