𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Determinants of repressor/operator recognition from the structure of the trp operator binding site

✍ Scribed by Shakked, Z.; Guzikevich-Guerstein, G.; Frolow, F.; Rabinovich, D.; Joachimiak, A.; Sigler, P. B.


Book ID
109788146
Publisher
Nature Publishing Group
Year
1994
Tongue
English
Weight
886 KB
Volume
368
Category
Article
ISSN
0028-0836

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Flexibility of dna binding domain of trp
✍ Michael R. Gryk; Oleg Jardetzky; Lisa S. Klig; Charles Yanofsky πŸ“‚ Article πŸ“… 2008 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 279 KB

## Abstract __Trp__ repressor (25 kDa) is a regulatory protein that controls transcription initiation in the tryptophan biosynthetic operon and at least four other operons in __Escherichia coli__. An alanine to valine mutation (AV77) in the DNA binding domain is known to increase repressor activity

Binding of Escherichia coli lexA repress
✍ Sandra L. Shaner; Elisabeth S. Gaissarian πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 684 KB

Equilibrium binding of Escherichia coli LexA repressor to the recA operator was studied by the polyacrylamide gel mobility shift assay as a function of solution conditions. In the presence of NsCl at 20"C, there was a significant salt dependence in binding to the recA operator, typical for protein-n

A model for the binding of lac repressor
✍ G. V. Gursky; V. G. Tumanyan; A. S. Zasedatelev; A. L. Zhuze; S. L. Grokhovsky; πŸ“‚ Article πŸ“… 1976 πŸ› Springer 🌐 English βš– 514 KB

A model is suggested for the lac repressor binding to the lac operator in which the repressor polypeptide chain sequences from Gly 14 to Ala 32 and from Ala 53 to Leu 71 are involved in specific interaction with operator DNA. A correspondence between the protein and DNA sequences is found which expl