Structure of rat aldose reductase-like p
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Krithika Sundaram; Urmi Dhagat; Satoshi Endo; Roland Chung; Toshiyuki Matsunaga;
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Article
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2011
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Elsevier Science
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English
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Rat aldose reductase-like protein (AKR1B14) is the ortholog of mouse vas deferens protein (AKR1B7) playing roles in detoxification of reactive aldehydes and synthesis of prostaglandin F 2a . The crystal structure of the binary complex (AKR1B14-NADPH) was determined at 1.86 ร resolution, and showed t