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Probing the Efficiency of N-Heterocyclic Carbene Promoted O - to C-Carboxyl Transfer of Oxazolyl Carbonates

✍ Scribed by Thomson, Jennifer E.; Campbell, Craig D.; Concellón, Carmen; Duguet, Nicolas; Rix, Kathryn; Slawin, Alexandra M. Z.; Smith, Andrew D.


Book ID
121297941
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
175 KB
Volume
73
Category
Article
ISSN
0022-3263

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Isothiourea-Mediated Asymmetric O- to C-
✍ Caroline Joannesse; Craig P. Johnston; Louis C. Morrill; Philip A. Woods; Madele 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 773 KB

## Abstract The structural motif within a series of tetrahydropyrimidine‐based isothioureas necessary for generating high asymmetric induction in the asymmetric Steglich rearrangement of oxazolyl carbonates is fully explored, with crossover and dynamic ^19^F NMR experiments used to develop a mechan