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Probing the calcium-induced conformational transition of troponin C with site-directed mutants

✍ Scribed by Fujimori, K.; Sorenson, M.; Herzberg, O.; Moult, J.; Reinach, F. C.

Book ID
109763531
Publisher
Nature Publishing Group
Year
1990
Tongue
English
Weight
342 KB
Volume
345
Category
Article
ISSN
0028-0836

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πŸ“œ SIMILAR VOLUMES

The kinetic cycle of cardiac troponin C:
The kinetic cycle of cardiac troponin C: Calcium binding and dissociation at site II trigger slow conformational rearrangements
✍ Andrea L. Hazard; Susy C. Kohout; Nicole L. Stricker; John A. Putkey; Joseph J. πŸ“‚ Article πŸ“… 1998 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 983 KB

## Abstract The goal of this study is to characterize the kinetic mechanism of Ca^2+^ activation and inactivation of cardiac troponin C (cTnC), the Ca^2+^ signaling protein which triggers heart muscle contraction. Previous studies have shown that IAANS covalently coupled to Cys84 of wild‐type cTnC