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Probes for the cocaine receptor. Potentially irreversible ligands for the dopamine transporter

โœ Scribed by Carroll, F. Ivy; Gao, Yigong; Abraham, Philip; Lewin, Anita H.; Lew, Robert; Patel, Amrat; Boja, John W.; Kuhar, Michael J.


Book ID
127092591
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
660 KB
Volume
35
Category
Article
ISSN
0022-2623

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โœ Alexander E. Morgan; Simone P. Porter; Francis A. Clarkson; Nora D. Volkow; Joan ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 72 KB

Using in vivo microdialysis techniques, the effects of RTI-55 and/or cocaine on extracellular dopamine (DA) concentrations were measured in the nucleus accumbens (NACC) of freely moving rats. In control animals, cocaine (20 mg/kg) increased NACC DA approximately 458% 60 minutes following administrat