𝔖 Bobbio Scriptorium
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BP 897, a Selective Dopamine D3 Receptor Ligand with Therapeutic Potential for the Treatment of Cocaine-Addiction

✍ Scribed by F. J. Garcia-Ladona; B. F. Cox


Book ID
109105617
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
134 KB
Volume
9
Category
Article
ISSN
1080-563X

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A novel series of arylpiperazines with h
✍ P. John Murray; Lee A. Harrison; Martin R. Johnson; Graeme M. Robertson; David I πŸ“‚ Article πŸ“… 1995 πŸ› Elsevier Science 🌐 English βš– 210 KB

A novel series of arylpiperazines has been synthesised which show high affinity for dopamine D 3 receptors. Several of these compounds exhibit ca. 100 fold selectivity for the dopamine D 3 receptor over D 1 , D 2 and D 4 receptors. In vivo studies suggest that 4 (GR103691) may have an atypical antip