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Probes for narcotic receptor mediated phenomena. 10. Irreversible ligands to opioid receptors based on biologically potent endoethenooripavines. Reversible binding of fit to mu and delta opioid receptors

โœ Scribed by R.A Lessor; K.C Rice; R.A Streaty; W.A Klee; A.E Jacobson

Book ID
119073353
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
303 KB
Volume
5
Category
Article
ISSN
0143-4179

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๐Ÿ“œ SIMILAR VOLUMES

Probes for narcotic receptor mediated ph
Probes for narcotic receptor mediated phenomena 8. Tritiation of irreversible mu or delta specific opioid receptor affinity ligands to high specific activity
โœ Terrence R. Burke Jr.; Kenner C. Rice; Arthur E. Jacobson; William F. Simonds; W ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 381 KB

Tritiation of the delta-specific opioid alkylating ligand FIT, 3 and the mu-specific opioid alkylating ligand BIT, 2 to high specific activity is described. Both compounds were derived from dibrominated amino intermediates (4 and lo, respectively) which were tritiated with tritium gas over Pd/C befo