𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ProbABEL package for genome-wide association analysis of imputed data

✍ Scribed by Yurii S Aulchenko; Maksim V Struchalin; Cornelia M van Duijn

Book ID
114999111
Publisher
BioMed Central
Year
2010
Tongue
English
Weight
302 KB
Volume
11
Category
Article
ISSN
1471-2105

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Imputation aware meta-analysis of genome
Imputation aware meta-analysis of genome-wide association studies
✍ Noah Zaitlen; Eleazar Eskin πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 280 KB πŸ‘ 2 views

## Abstract Genome‐wide association studies have recently identified many new loci associated with human complex diseases. These newly discovered variants typically have weak effects requiring studies with large numbers of individuals to achieve the statistical power necessary to identify them. Lik

The use of imputed values in the meta-an
The use of imputed values in the meta-analysis of genome-wide association studies
✍ Shuo Jiao; Li Hsu; Carolyn M. Hutter; Ulrike Peters πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 178 KB πŸ‘ 2 views

In genome-wide association studies (GWAS), it is a common practice to impute the genotypes of untyped single nucleotide polymorphism (SNP) by exploiting the linkage disequilibrium structure among SNPs. The use of imputed genotypes improves genome coverage and makes it possible to perform meta-analys

GENOMIZER: an integrated analysis system
GENOMIZER: an integrated analysis system for genome-wide association data
✍ Andre Franke; Andreas Wollstein; Markus Teuber; Michael Wittig; Tim Lu; Katrin H πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 587 KB

## Communicated by Pui-Yan Kwok Genome-wide association analysis appears to be a promising way to identify heritable susceptibility factors for complex human disorders. However, the feasibility of large-scale genotyping experiments is currently limited by an incomplete marker coverage of the genom