## Abstract Genomeβwide scans of nucleotide variation in human subjects are providing an increasing number of replicated associations with complex disease traits. Most of the variants detected have small effects and, collectively, they account for a small fraction of the total genetic variance. Ver
β¦ LIBER β¦
Missing data imputation and haplotype phase inference for genome-wide association studies
β Scribed by Sharon R. Browning
- Book ID
- 106134751
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 253 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0340-6717
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## Abstract The large number of markers considered in a genomeβwide association study (GWAS) has resulted in a simplification of analyses conducted. Most studies are analyzed one marker at a time using simple tests like the trend test. Methods that account for the special features of genetic associ