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Pro12Ala mutation in the peroxisome proliferator-activated receptor γ2 (PPARγ2) and severe obesity: a case–control study

✍ Scribed by Vaccaro, O; Mancini, F P; Ruffa, G; Sabatino, L; Colantuoni, V; Riccardi, G


Book ID
110044453
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
90 KB
Volume
24
Category
Article
ISSN
1476-5497

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Background Peroxisome proliferators-activated receptor γ (PPAR γ ) is a nuclear hormone receptor that serves as a master regulator of adipocytesspecific genes contributing to adipocytes differentiation, susceptibility to obesity, and insulin sensitivity. The substitution of proline to alanine at cod