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Pro-Inflammatory Cytokines Induce Expression of Matrix-Metabolizing Enzymes in Human Cervical Smooth Muscle Cells

✍ Scribed by Michiko Watari; Hidemichi Watari; Michael E. DiSanto; Samuel Chacko; Guo-Ping Shi; Jerome F. Strauss III

Book ID: 117022711
Publisher: American Society for Investigative Pathology
Year: 1999
Tongue: English
Weight: 699 KB
Volume: 154
Category: Article
ISSN: 0002-9440
DOI: 10.1016/s0002-9440(10)65431-4

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## Abstract The expression of matrix metalloproteinase‐9 (MMP‐9) has been implicated in progression of atherosclerotic lesions. The role and importance of the signaling pathway in the transcriptional regulation of MMP‐9 in human aortic smooth muscle cells (HASMC) was examined. Tumor necrosis factor