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Pro-apoptotic interactions between XK469 and the peripheral benzodiazepine receptor

✍ Scribed by David Kessel; Jerome P. Horwitz

Book ID
117466946
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
183 KB
Volume
168
Category
Article
ISSN
0304-3835

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## Abstract The ASPP proteins are apoptosis regulators: ASPP1 and ASPP2 promote, while iASPP inhibits, apoptosis. The mechanism by which these different outcomes are achieved is still unknown. The C‐terminal ankyrin repeats and SH3 domain (ANK‐SH3) mediate the interactions of the ASPP proteins with