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Functional interaction between the pro-apoptotic DAP3 and the glucocorticoid receptor

✍ Scribed by Sanna M Hulkko; Johanna Zilliacus


Book ID
117052185
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
288 KB
Volume
295
Category
Article
ISSN
0006-291X

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## Abstract The ASPP proteins are apoptosis regulators: ASPP1 and ASPP2 promote, while iASPP inhibits, apoptosis. The mechanism by which these different outcomes are achieved is still unknown. The C‐terminal ankyrin repeats and SH3 domain (ANK‐SH3) mediate the interactions of the ASPP proteins with