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PRNP Val129 homozygosity increases risk for early-onset Alzheimer's disease

โœ Scribed by Bart Dermaut; Esther A. Croes; Rosa Rademakers; Marleen Van Den Broeck; Marc Cruts; Albert Hofman; Cornelia M. Van Duijn; Christine Van Broeckhoven


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
67 KB
Volume
53
Category
Article
ISSN
0364-5134

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โœ W. K. Scott; A. M. Saunders; P. C. Gaskell; P. A. Locke; J. H. Growdon; L. A. Fa ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 352 KB ๐Ÿ‘ 1 views

We examined the association of apolipoprotein E (ApoE) genotype and the risk of early-onset Alzheimer's disease (AD) in 209 white early-onset sporadic cases (43% male) and 303 white controls (48% male) of similar age distribution. The risk of AD was significantly increased, relative to the 313 genot