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Prion protein fragment 106–126-induces astroglial proliferation through the activation of l-type calcium channels

✍ Scribed by T. Florio; M. Grimaldi; A. Scorziello; M. Fattore; M. Salmona; O. Bugiani; F. Tagliavini; G. Forloni; G. Schettini


Book ID
119179796
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
150 KB
Volume
31
Category
Article
ISSN
1043-6618

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Prion protein fragment 106–126 induces a
✍ Tullio Florio; Stefano Thellung; Carolina Amico; Mauro Robello; Mario Salmona; O 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 358 KB 👁 1 views

The prion diseases are transmissible neurodegenerative pathologies characterized by the accumulation of altered forms of the prion protein (PrP), termed PrP Sc , in the brain. Previous studies have shown that a synthetic peptide homologous to residues 106-126 of PrP (PrP 106-126) maintains many char