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Principles Underlying the Development and Use of Live Attenuated Cold-Adapted Influenza A and B Virus Vaccines

โœ Scribed by Murphy, Brian R.; Coelingh, Kathleen

Book ID
120811369
Publisher
Mary Ann Liebert
Year
2002
Tongue
English
Weight
460 KB
Volume
15
Category
Article
ISSN
0882-8245

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โœ Hunein F. Maassab; Martin L. Bryant ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 103 KB ๐Ÿ‘ 1 views

A procedure to attenuate live influenza virus of type A and type B was developed using adaptation of the virus to grow at 25 degrees C (cold adaptation; ca). Through a series of stepwise passages, two stable mutants were obtained and designated as 'Master' strains, one for type A influenza virus (A/