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Development and characterization of a live attenuated influenza B virus vaccine candidate

โœ Scribed by Sang-Uk Seo; Young-Ho Byun; Eun-Young Lee; Eun-Ju Jung; Yo Han Jang; Hyun-Ah Kim; Suk-Hoon Ha; Kwang-Hee Lee; Baik Lin Seong


Book ID
116960284
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
492 KB
Volume
26
Category
Article
ISSN
0264-410X

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A procedure to attenuate live influenza virus of type A and type B was developed using adaptation of the virus to grow at 25 degrees C (cold adaptation; ca). Through a series of stepwise passages, two stable mutants were obtained and designated as 'Master' strains, one for type A influenza virus (A/