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Primary mitogenic action of N-methyl-N-nitro-N-nitrosoguanidine (MNNG)

✍ Scribed by Ziebarth, D.; Urban, H.; Schmidt, A.; Danz, M.


Book ID
122794267
Publisher
Elsevier
Year
1977
Weight
399 KB
Volume
14
Category
Article
ISSN
0014-4908

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## Abstract Using an organ culture/cell culture system, we transformed rat tracheal epithelial cells __in vitro__ by exposure to MNNG. Ten tracheal organ cultures per group were exposed twice (at days 3 and 6) to 0,0.001, 1.0 or 10.0 ΞΌg MNNG/ml of medium. Following this exposure, the explants were