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Carcinogenic effect of N-methyl-N′-nitro-N-nitrosoguanidine (MNNG) in European hamsters

✍ Scribed by Ketkar, M.; Reznik, G.; Green, U.

Book ID: 122009528
Publisher: Elsevier Science
Year: 1978
Tongue: English
Weight: 216 KB
Volume: 4
Category: Article
ISSN: 0304-3835
DOI: 10.1016/S0304-3835(78)94842-5

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## Abstract Using an organ culture/cell culture system, we transformed rat tracheal epithelial cells __in vitro__ by exposure to MNNG. Ten tracheal organ cultures per group were exposed twice (at days 3 and 6) to 0,0.001, 1.0 or 10.0 μg MNNG/ml of medium. Following this exposure, the explants were