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Primary laryngeal lymphoma: Report of 3 cases and review of the literature

✍ Scribed by Konstantinos Markou; John Goudakos; John Constantinidis; Ioannis Kostopoulos; Victor Vital; Angelos Nikolaou

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
903 KB
Volume
32
Category
Article
ISSN
1043-3074

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✦ Synopsis

Abstract

Background

Extranodal lymphomas limited to the larynx are rare, accounting for less than 1% of all laryngeal neoplasms. The aim of this study was to report the experience of our department in the management of these aggressive lesions, as they require special diagnostic and therapeutic attention.

Methods

The case records of 3 patients with the diagnosis of lymphoma involving the larynx were retrospectively reviewed.

Results

The histopathological diagnosis revealed 1 case of marginal zone lymphoma mucosa‐associated lymphoid tissue type, 1 case of T‐lymphoblastic lymphoma, and 1 case of a rare coexistence of in situ squamous cell carcinoma with an isolated intravascular (angioimmunoblastic) lymphoma of peripheral T‐cell origin. Details of the presentation, diagnostic procedures, treatment, and outcome of these patients were presented.

Conclusions

Primary laryngeal lymphoma is a rare entity. Early symptoms are subtle and nonspecific, and confirmation of the diagnosis is often difficult. Because of the rarity of this tumor type, the optimal management remains controversial and it seems that should be managed not as a distinct disease entity but as an unusual presentation of non‐Hodgkin lymphoma, according to the recent treatment trends. © 2009 Wiley Periodicals, Inc. Head Neck, 2010

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