The relationship between sonic Hedgehog
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Jennifer N. Murdoch; Andrew J. Copp
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Article
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2010
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John Wiley and Sons
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English
β 530 KB
## Abstract The Hedgehog signaling pathway is essential for many aspects of normal embryonic development, including formation and patterning of the neural tube. Absence of the sonic hedgehog (shh) ligand is associated with the midline defect holoprosencephaly, whereas increased Shh signaling is ass