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Cilia and mammalian hedgehog signaling

โœ Scribed by C.Y. Su; C.E. Larkins; M.J. Hillman; T. Caspary


Book ID
116552150
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
43 KB
Volume
28
Category
Article
ISSN
0736-5748

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## Abstract The Hedgehog signaling pathway is essential for many aspects of normal embryonic development, including formation and patterning of the neural tube. Absence of the sonic hedgehog (shh) ligand is associated with the midline defect holoprosencephaly, whereas increased Shh signaling is ass