## Abstract ## BACKGROUND According to the overview of Early Breast Cancer Trialists' Collaborative Group, anthracycline containing regimens are superior to cyclophosphamide, methotrexate, and 5βfluorouracil (CMF) as adjuvant chemotherapy for breast carcinoma, but no comparative information is ava
Primary chemotherapy with cyclophosphamide, methotrexate, and 5-fluorouracil in operable breast carcinoma
β Scribed by Catalina Falo; Abelardo Moreno; Enrique Benito; Belen Lloveras; Mar Varela; Jose Ma Serra; Luis Prieto; Diego Azpeitia; Agustin Escobedo
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 162 KB
- Volume
- 103
- Category
- Article
- ISSN
- 0008-543X
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Thirty-eight patients with metastatic colorecal carcinoma were treated with 5-fluorouracil (5-FU), and 38 patients were treated with the combination of 5-FU, cyclophosphamide, and methotrexate. In terms of percent response, response duration, and survival there was no apparent difference between the
Twenty-nine patients with metastatic breast cancer were treated with fluorouracil, adriamycin, cyclophosphamide (FAC), and methotrexate (MTX), with or without leukovorin rescue. Of 24 evaluable patients, one achieved a complete remission and 17 had partial responses. The overall objective response r
## Background: The current study was conducted to assess the toxicity of concurrent adjuvant cyclophosphamide, methotrexate, and 5-fluorouracil (cmf) chemotherapy and radiotherapy (rt) for early breast carcinoma. ## Methods: In the current study, the authors reviewed the records of 680 consecutiv