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Preventive effect of epicatechin and ginsenoside Rb2 on the inhibition of gap junctional intercellular communication by TPA and H2O2

✍ Scribed by Kyung-Sun Kang; Byeong-Cheol Kang; Beom-Jun Lee; Jeong-Hwan Che; Guang-Xun Li; James E. Trosko; Yong-Soon Lee


Book ID
117469791
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
780 KB
Volume
152
Category
Article
ISSN
0304-3835

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Inhibition of connexin43 gap junctional
✍ Randall J. Ruch; James E. Trosko; Burra V. Madhukar πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 243 KB

## Abstract The phorbol ester, 12‐__O__‐tetradecanoylphorbol‐13‐acetate (TPA), is a potent inhibitor of gap junctional intercellular communication (GJIC). This inhibition requires activation of protein kinase C (PKC), but the events downstream of this kinase are not known. Since PKC can activate ex