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Prevention of experimental autoimmune diabetes in mice by treatment with leflunomide

✍ Scribed by S Stosic-Grujicic; M Dimitrijevic; R.R Bartlett

Book ID
117237192
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
226 KB
Volume
30
Category
Article
ISSN
0041-1345

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Prevention of autoimmune diabetes in NOD
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✍ C. Mathieu; M. Waer; J. Laureys; O. Rutgeerts; R. Bouillon πŸ“‚ Article πŸ“… 1994 πŸ› Springer 🌐 English βš– 794 KB

1,25 dihydroxyvitamin D3, the active form of vitamin D, has immunomodulatory properties in vitro and in vivo. We report that treatment with 1,25 dihydroxyvitamin 03 (5 gg/kg on alternate days) prevents the development of clinical diabetes in NOD mice, an animal model of human autoimmune diabetes. Di