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Prevention of calcification of bioprosthetic heart valve leaflets by Ca2+ diphosphonate pretreatment

✍ Scribed by Thomas P. Johnston; Frederick J. Schoen; Robert J. Levy

Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
1002 KB
Volume
77
Category
Article
ISSN
0022-3549

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## Abstract Glutaraldehyde crosslinked bioprosthetic heart valves (BHVs) have two modalities of failure: degeneration (cuspal tear due to matrix failure) and calcification. They can occur independently as well as one can lead to the other causing co‐existence. Calcific failure has been extensively