Fhit gene alterations in hepatocarcinoge
β
Toshifumi Tsujiuchi; Yasutaka Sasaki; Yasuo Oka; Yoichi Konishi; Masahiro Tsutsu
π
Article
π
2003
π
John Wiley and Sons
π
English
β 125 KB
## Abstract Alterations of the fragile histidine triad (__Fhit__) gene were investigated in rat hepatocarcinogenesis induced by a cholineβdeficient Lβamino acidβdefined (CDAA) diet. Males of the F344 strain, 6 wk of age, were fed a CDAA diet, and subgroups were killed at 2, 4, 12, 20, and 75 wk aft