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Prevention and treatment of Lewis rat experimental allergic encephalomyelitis with a monoclonal antibody to the T cell receptor Vβ8.2 segment

✍ Scribed by Horst Imrich; Christine Kugler; Nora Torres-Nagel; Rüdiger Dörries; Thomas Hünig


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
563 KB
Volume
25
Category
Article
ISSN
0014-2980

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Previous studies of experimental allergic encephalomyelitis (EAE) in the LER rat have suggested that amino acid differences present in the LER TCR Vp8.2 chain may be associated with disease resistance. We report here that LEW rats bred to express a Vp8.2 gene from DA rats, identical to that found in