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Prevalence of the Methylenetetrahydrofolate Reductase (MTHFR) C677T Mutation in Patients with Varicose Veins of Lower Limbs

✍ Scribed by A.M. Sverdlova; N.A. Bubnova; S.S. Baranovskaya; V.I. Vasina; A.O. Avitisjan; E.I. Schwartz

Book ID: 115639343
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 54 KB
Volume: 63
Category: Article
ISSN: 1096-7192
DOI: 10.1006/mgme.1997.2638

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The polymorphic mutation C677T in the gene of MTHFR is considered a risk mutation for spina bifida and vascular disease. Another common mutation on the MTHFR gene, A1298C, has also been described as another risk mutation. We studied the frequencies of these two mutations on DNA samples from healthy