Prevalence of the methylenetetrahydrofolate reductase 677C > T mutation in the Mediterranean Spanish population. Association with cardiovascular risk factors
✍ Scribed by M. Guillén; D. Corella; O. Portolés; J.I. González; F. Mulet; C. Sáiz
- Book ID
- 110368206
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 106 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0393-2990
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The polymorphic mutation C677T in the gene of MTHFR is considered a risk mutation for spina bifida and vascular disease. Another common mutation on the MTHFR gene, A1298C, has also been described as another risk mutation. We studied the frequencies of these two mutations on DNA samples from healthy
## Abstract ## Objectives/Hypothesis: To investigate the recently reported association of the C677T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene with sudden sensorineural hearing loss (SSNHL), we analyzed data from a community‐based Japanese population. ## Study Design: N