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Prevalence of the I1307K APC gene variant in Israeli Jews of differing ethnic origin and risk for colorectal cancer

✍ Scribed by Paul Rozen*; ‡; Ruth Shomrat§; Hana Strul*; ‡; Tova Naiman§; Nataly Karminsky∥; Cyril Legum§; ‡; Avi Orr-Urtreger§; ‡

Book ID
118521826
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
859 KB
Volume
116
Category
Article
ISSN
0016-5085

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Clinical and screening implications of the I1307K adenomatous polyposis coli gene variant in Israeli Ashkenazi Jews with familial colorectal neoplasia : Evidence for a founder effect
✍ Paul Rozen; Tova Naiman; Hana Strul; Philipp Taussky; Nataly Karminsky; Ruth Sho 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 92 KB 👁 1 views

## Abstract ## BACKGROUND The authors previously found the I1307K adenomatous polyposis coli (__APC__) gene variant in 5% of Ashkenazi control participants, in 15.4% of those who had familial colorectal neoplasia, but also in 1.6% of non‐Ashkenazi control participants. In this study, they evaluate