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I1307K APC gene variant has no clinical implication in Israeli jews at average or high risk for colorectal neoplasia

✍ Scribed by Hana Strul; Erez Birenbaum; Baruch Stern; Dina Kazanov; Livia Theodor; Yehudit Knaani; Yaara Degani; Zamir Halpern; Nadir Arber

Book ID: 119429454
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 355 KB
Volume: 120
Category: Article
ISSN: 0016-5085
DOI: 10.1016/s0016-5085(08)80592-6

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## Abstract ## BACKGROUND The authors previously found the I1307K adenomatous polyposis coli (__APC__) gene variant in 5% of Ashkenazi control participants, in 15.4% of those who had familial colorectal neoplasia, but also in 1.6% of non‐Ashkenazi control participants. In this study, they evaluate