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Prevalence of mutations of the NOD2/CARD15 gene and relation to phenotype in Spanish patients with Crohn disease

✍ Scribed by Mendoza, J. L.; Murillo, L. S.; Fernández, L.; Peña, A. S.; Lana, R.; Urcelay, E.; Cruz‐Santamaría, D. M.; de la Concha, E. G.; Díaz‐Rubio, M.; García‐Paredes, J.

Book ID
121277876
Publisher
Informa plc
Year
2003
Tongue
English
Weight
97 KB
Volume
38
Category
Article
ISSN
0036-5521

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Novel CARD15/NOD2 mutations in Finnish p
Novel CARD15/NOD2 mutations in Finnish patients with Crohn's disease and their relation to phenotypic variation in vitro and in vivo
✍ Maarit Lappalainen; Paulina Paavola-Sakki; Leena Halme; Ulla Turunen; Martti Fär 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 172 KB

## Background: Three mutations (r702w, g908r, and 1007fs) of the card15/nod2 gene associate with crohn's disease (cd). despite a strong linkage of cd to the inflammatory bowel disease (ibd) 1 region, only 16% of the finnish cd patients carry 1 of these 3 mutations, pointing to the possibility of ye