Prevalence of HTLV-I in arctic regions

✍ Scribed by Marjorie Robert-Guroff; Jeffrey Clark; Anne P. Lanier; Gunhild Beckman; Mads Melbye; Peter Ebbesen; William A. Blattner; Robert C. Gallo

• Publisher: John Wiley and Sons
• Year: 1985
• Tongue: French
• Weight: 508 KB
• Volume: 36
• Category: Article
• ISSN: 0020-7136
• DOI: 10.1002/ijc.2910360605

✦ Synopsis

Sera of native inhabitants of Arctic regions were

In 1982 we reported the isolation of a new HTLV assayed for antibodies to HTLV-I by the ELlSA techsubtype, termed HTLV-11, from cells of a patient with firm antibody specificity. Residents of 7 widely separated Alaskan villages exhibited prevalence rates anaraman et al. t 1982). HTLV-11 is readily distinof 0 to I ~o / ~ for HTLV-I antibodies. L~~~ than I 01~ of guishable from HTLV-I by immunologic and molecular Greenland Eskimos were HTLV-I antibody-positive. biologic Criteria, but iS ak0 Clearly related to the pro-Residents of 3 northern Swedish regions ranged in totype virus by these same criteria. An additional HTLV-I antibody prevalence from 0 to 5%. Sera of HTLV-I1 isolate has been obtained from cells of an healthy native inhabitants of Alaska and northern intravenous drug user, who died of AIDS (Hahn et al., Sweden were similarly assayed for antibodies to 1984). However, except in sera of i.v. drug abusers HTLV-II. No additional sera were shown to be positive Robert-Guroff, unpublished), no for HTLV-II antibodies. While some of the HTLV-I evidence of widespread infection by HTLV-II has been