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Prevalence of factor V Leiden in south Tunisian blood donors

✍ Scribed by Lobna Maalej; Basma Hadjkacem; Ikram Ben Amor; Mariem Smaoui; Ali Gargouri; Jalel Gargouri

Book ID
106544443
Publisher
Springer US
Year
2011
Tongue
English
Weight
199 KB
Volume
32
Category
Article
ISSN
0929-5305

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Resistance to activated protein C (APC) is the most common inherited risk factor for venous thrombosis. Most cases of APC resistance are caused by the point mutation nt 1691 G-A in factor V gene, referred to as factor V Leiden mutation. As initially shown in a Dutch population, this mutation has a c