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Prevalence of a family history of dementia in patients with early and late onset Alzheimer's disease


Book ID
123319076
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
138 KB
Volume
11
Category
Article
ISSN
0197-4580

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Validity of family history for the diagn
โœ G. Devi; K. Marder; P.W. Schofield; M.X. Tang; Y. Stern; R. Mayeux ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 31 KB ๐Ÿ‘ 2 views

We examined 180 siblings of 127 probands with probable or possible Alzheimer's dementia (AD) in a family study of AD. The overall sensitivity of a simple family history questionnaire was 64% and the specificity was 84%. Sensitivity improved 90-100% with minimal decline in specificity when we conside