## Abstract We determined the prevalence of two common leucine‐rich repeat kinase 2 (LRRK2) gene mutations in Australian patients with Parkinson's disease (PD). Of 830 affected patients, eight were heterozygous for the G2019S mutation, and two were heterozygous for the R1441H (4,322 G > A) mutation
✦ LIBER ✦
Prevalence and clinical features of LRRK2 mutations in patients with Parkinson’s disease in southern Spain
✍ Scribed by L. Gao; P. Gómez-Garre; F. J. Díaz-Corrales; F. Carrillo; M. Carballo; A. Palomino; J. Díaz-Martín; R. Mejías; P. J. Vime; J. López-Barneo; P. Mir
- Book ID
- 111065952
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 75 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1351-5101
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## Abstract Mutations in the leucine‐rich repeat kinase 2 (__LRRK2__) gene are the most common genetic determinant of Parkinson's disease (PD) in European‐derived populations, but far less is known about __LRRK2__ mutations and susceptibility alleles in Asians. To address this issue, we sequenced t