Pretreatment intrahepatic CD8+ cell number correlates with virological response to antiviral therapy in chronic hepatitis C
β Scribed by J.M. Vrolijk; H.L.A. Janssen; J. Kwekkeboom; B.E. Hansen; P. Zondervan; A.D.M.E. Osterhaus; S.W. Schalm; B.L. Haagmans
- Book ID
- 117372756
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 143 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0168-8278
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## Abstract Recognition of HBVβinfected hepatocytes by CD8 Tβlymphocytes is important for viral clearance. Expression of hepatitis B core antigen (HBcAg) in HBVβinfected hepatocytes can trigger this antiviral Tβcell response. The intrahepatic CD8 Tβlymphocytes and HBcAg expression were investigated
CORRESPONDENCE 1287 tive anions determine the potential for crystal precipi-though the location within the stone is not identified. Thus, their data would seem to confirm our findings tation within bile. Certain disease states predispose and be in conflict with the statement in their letter to supe