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Pretargeted tumour imaging with streptavidin immunoconjugates of monoclonal antibody CC49 and 111In-DTPA-biocytin

✍ Scribed by Teresa M. Alvarez-Diez; Jeannie Polihronis; Raymond M. Reilly


Book ID
116172135
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
1007 KB
Volume
23
Category
Article
ISSN
0969-8051

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Monoclonal antibody 2G3 directed against a high molecular weight glycoprotein on breast and ovarian cancer cells was conjugated with bicyclic DTPA (or EDTA) anhydride or benzyl isothiocyanate DTPA (benzyl DTPA) and labeled with 111In. DTPA anhydride was more reactive with the antibody than benzyl DT