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Presynaptic localization of a truncated isoform of the type 2 corticotropin releasing factor receptor in the cerebellum

โœ Scribed by J.B. Tian; X. Shan; G.A. Bishop; J.S. King


Book ID
116787535
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
945 KB
Volume
138
Category
Article
ISSN
0306-4522

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Evidence for the presence of the type 2
โœ Georgia A. Bishop; Jin Bin Tian; Jennifer J. Stanke; Andy J. Fischer; James S. K ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 989 KB

## Abstract Corticotropin releasing factor (CRF), localized in afferent inputs to the cerebellum, binds to two receptors defined as the Type 1 (CRFโ€R1) and the Type 2 (CRFโ€R2ฮฑ). CRFโ€R1 has been localized to the cerebellum, as has a truncated isoform of CRFโ€R2ฮฑ. Evidence for the presence of the full

Cellular localization of the full-length
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## Abstract Corticotropin releasing factor (CRF) and its cognate receptors, defined as Type 1 and Type 2 have been localized within the cerebellum. The Type 2 CRF receptor (CRFโ€R2) is known to have both a full length (CRFโ€R2ฮฑ) and a truncated (CRFโ€R2ฮฑโ€tr) isoform. A recent study documented CRFโ€R2ฮฑ