Presynaptic localization of a truncated isoform of the type 2 corticotropin releasing factor receptor in the cerebellum
โ Scribed by J.B. Tian; X. Shan; G.A. Bishop; J.S. King
- Book ID
- 116787535
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 945 KB
- Volume
- 138
- Category
- Article
- ISSN
- 0306-4522
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## Abstract Corticotropin releasing factor (CRF), localized in afferent inputs to the cerebellum, binds to two receptors defined as the Type 1 (CRFโR1) and the Type 2 (CRFโR2ฮฑ). CRFโR1 has been localized to the cerebellum, as has a truncated isoform of CRFโR2ฮฑ. Evidence for the presence of the full
## Abstract Corticotropin releasing factor (CRF) and its cognate receptors, defined as Type 1 and Type 2 have been localized within the cerebellum. The Type 2 CRF receptor (CRFโR2) is known to have both a full length (CRFโR2ฮฑ) and a truncated (CRFโR2ฮฑโtr) isoform. A recent study documented CRFโR2ฮฑ