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Presynaptic and axonal expression of the Fragile X mental retardation protein in the developing and regenerating CNS

✍ Scribed by S.B. Christie; J. Schwob; J.R. Fallon


Book ID
116551455
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
37 KB
Volume
24
Category
Article
ISSN
0736-5748

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Fragile X mental retardation results from the absence of a selective RNA-binding protein, FMRP. Previous studies demonstrated that FMRP forms messenger ribonucleoprotein (mRNP) complexes to associate with translating polyribosomes, suggesting that FMRP is involved in regulating protein synthesis. We