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Preserving effect of orally administered clodronate on bone mineral density and bone geometry in ovariectomized rats

✍ Scribed by T. Österman; L. Laurén; R. Hannuniemi; P. Kuurtamo; R. Sellman; Leiras Oy

Publisher
Springer-Verlag
Year
1996
Tongue
English
Weight
136 KB
Volume
6
Category
Article
ISSN
0937-941X

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To determine whether the uterus plays any role in mediating the ability of estrogen to conserve bone in the rat, eight groups of animals (n = 8) with their skeletons labeled with 45Ca were studied. Rats were ovariectomized (OVX), hysterectomized (Hyst), or given sham operations (Sham) and then pair-