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Preserved expression of fibroblast growth factor (FGF)-2 and FGF receptor 1 in brain and spinal cord of amyotrophic lateral sclerosis patients

✍ Scribed by Susanne Petri; Klaus Krampfl; Kerstin Kuhlemann; Reinhard Dengler; Claudia Grothe


Publisher
Springer
Year
2008
Tongue
English
Weight
932 KB
Volume
131
Category
Article
ISSN
1432-119X

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In response to peripheral nerve lesion, synthesis of basic fibroblast growth factor (FGF-2) increases in sensory ganglia and motoneurons. Here, we investigated the axotomy-induced regulation of FGF-2 and FGF receptor-1 (FGFR-1) expression in the autonomic nervous system using the sympathetic superio