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Presence of isochromosome 7q in Wilms' tumor as the sole change

✍ Scribed by T.L. Pool; A.L. Saunders; R. Morgan; J.F. Stone; M.M. Cavanaugh; S.Y. Dong; A.M. Meloni; A.A. Sandberg

Book ID
114136709
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
117 KB
Volume
98
Category
Article
ISSN
0165-4608

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## Abstract Loss of heterozygosity (LOH) on chromosome arm 7q31 is found in many prostate tumors. Such alterations are generally associated with inactivation of tumor suppressor genes. It has been shown previously that the main region of LOH at 7q31 spans the interval between the D7S486 and D7S2460