✦ LIBER ✦

Presence of human papillomavirus type-16 and type-18 DNA sequences and their expression in cervical cancers and cell lines from japanese patients

✍ Scribed by Youko Tsunokawa; Naoko Takebe; Shiro Nozawa; Tatsuhiro Kasamatsu; Lutz Gissmann; Harald Zur Hausen; Masaaki Terada; Takashi Sugimura

Publisher: John Wiley and Sons
Year: 1986
Tongue: French
Weight: 808 KB
Volume: 37
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910370405

No coin nor oath required. For personal study only.

✦ Synopsis

Southern blot analyses of surgical specimens of cervical carcinoma from Japanese patients showed that 3/9 samples contained human papillomavirus (HPV) type-I6 DNA sequences, and 2 contained HPV type-I6 DNA sequences. By Northern blot analyses, RNA transcripts of HPV DNA sequences were demonstrated in some of the tissues containing HPV type-I6 or HPV type-I8 DNA sequences. Two cell lines established from cervical cancers of Japanese patients also contained HPV type-I6 genomes and these cell lines contained HPV type-I8 transcripts. Two other cervical cancer cell lines from a Japanese patient were found to contain HPV type-I6 DNA sequences and their RNA transcripts.

📜 SIMILAR VOLUMES

Sequence variation and physical state of

Sequence variation and physical state of human papillomavirus type 16 cervical cancer isolates from Australia and New Caledonia

✍ Kylie J. Watts; Carol H. Thompson; Yvonne E. Cossart; Barbara R. Rose 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 356 KB

## Abstract Sequence diversity over 2600 nucleotides of the upstream regulatory region (URR) and the __E6__ and __E2/E4__ genes of 34 human papillomavirus (HPV)16 cervical cancer isolates from Australia and New Caledonia was investigated. One 81 base duplication, 41 single base substitutions and 1

Antibodies against oncoproteins E6 and E

Antibodies against oncoproteins E6 and E7 of human papillomavirus types 16 and 18 in cervical-carcinoma patients from Russia

✍ Klaus Zumbach; Fjodor Kisseljov; Olga Sacharova; Gadzi Shaichaev; Ludmila Semjon 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 133 KB 👁 1 views

Certain human papillomaviruses (HPV), mainly types 16 and 18, have been widely recognized as an essential etiologic factor for the development of carcinoma of the uterine cervix. The early HPV proteins E6 and E7 are consistently expressed in the tumor cells, and cervical-carcinoma patients can devel

Prevalence and distribution of human pap

Prevalence and distribution of human papillomavirus type-16 DNA in pelvic lymph nodes of patients with cervical cancer and in women with no history of cervical abnormality

✍ Barbara R. Rose; Carol H. Thompson; Lorraine A. Chantrill; Martin H. N. Tattersa 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 French ⚖ 559 KB

The polymerase chain reaction (PCR) was used to investigate the prevalence and distribution of human papillomavirus (HPV)-I6 DNA in paraffin sections of all pelvic lymph nodes removed from 14 patients with Stage Ib-cervical cancer at the time of resection of their primary tumours. The results were c

Antibodies against human papillomavirus

Antibodies against human papillomavirus (HPV) type 16 and 18 E2, E6 and E7 proteins in sera: Correlation with presence of papillomavirus DNA

✍ Ricardo Rosales; Mario López-Contreras; Roberto Risco Cortes 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 142 KB 👁 1 views

## Abstract Human papillomavirus (HPV) infection is associated with cervical cancer. The E2 and E1 papillomavirus proteins are expressed at the early stage of infection and regulate DNA replication. The E2 protein activates and represses transcription from different HPVs promoters. At some stage wh

Human papillomavirus type 18 E6* MRNA in

Human papillomavirus type 18 E6* MRNA in primary tumors and pelvic lymph nodes of hungarian patients with squamous cervical cancer

✍ J. Czégledy; M. Evander; Z. Hernádi; L. Gergely; G. Wadell 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 868 KB

Seven biopsy specimens from squamous-cell carcinomas of the uterine cervix were examined by RT-PCR for humanpapilloma-virus(HPV)-specific transcripts. With our HPVl8transcription-specific primer pair (5' nts 127-149; 3' nts 587-607), all 7 were shown to contain one strong viral mRNA signal from the

Antibodies against oncoproteins E6 and E

Antibodies against oncoproteins E6 and E7 of human papillomavirus types 16 and 18 in patients with head-and-neck squamous-cell carcinoma

✍ Klaus Zumbach; Markus Hoffmann; Tomas Kahn; Franz Bosch; Stefan Gottschlich; Tib 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 69 KB 👁 1 views

Human papillomaviruses (HPVs) have been recognized as an essential pathogenic factor in anogenital cancer. HPV DNA has also been found in a subgroup of head-and-neck squamous-cell carcinomas (HNSCCs), and a causative role of the virus in the development of these tumors has been suggested by the conc