PreS1 deleted variants of hepatitis B virus in patients with chronic hepatitis
β Scribed by Etsuro Nakajima; Masahito Minami; Takahiro Ochiya; Keizo Kagawa; Takeshi Okanoue
- Book ID
- 118567139
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 488 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0168-8278
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The polymerase chain reaction (PCR) and DNA sequencing were used to examine genomic variation in the preβcore/core open reading frame of the hepatitis B virus (HBV) in chronically infected patients. Gel electrophoresis of amplification products showed the presence of shortened forms of
Hepatitis B surface antigen (HBsAg) and anti-HBs antibodies (anti-HBs) may coexist in certain chronic hepatitis B (CHB) patients. This study was designed to further explore the relationship between this coexistence and hepatitis B Virus (HBV) preS deletions. Sera of 28 patients carrying both HBsAg a