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Preproenkephalin mRNA in T-Cells, macrophages, and mast cells

✍ Scribed by J. Martin; M. B. Prystowsky; Dr. R. H. Angeletti

Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 617 KB
Volume: 18
Category: Article
ISSN: 0360-4012
DOI: 10.1002/jnr.490180114

No coin nor oath required. For personal study only.

✦ Synopsis

The presence of preproenkephalin mRNA in tumor cell lines derived from myeloid and mast cells was analyzed by RNA dot blot hybridization. A B-cell lymphoma was negative for preproenkephalin mRNA, but several T-cell lymphomas were positive. A mastocytoma and two macrophage cell lines were found to have high levels of preproenkephalin mRNA. Purified natural macrophages and mast cells also possessed easily detectable levels of this mRNA.

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