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Fractalkine and macrophage-derived chemokine: T cell-attracting chemokines expressed in T cell area dendritic cells

✍ Scribed by Nobuo Kanazawa; Tomoyuki Nakamura; Kei Tashiro; Masamichi Muramatsu; Kazumasa Morita; Kozo Yoneda; Kayo Inaba; Sadao Imamura; Tasuku Honjo


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
240 KB
Volume
29
Category
Article
ISSN
0014-2980

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Dendritic cells (DC) migrate into inflamed peripheral tissues where they capture antigens and, following maturation, to lymph nodes where they stimulate T cells. To gain insight into this process we compared chemokine receptor expression in immature and mature DC. Immature DC expressed CCR1, CCR2, C