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Preparative chromatographic resolution of racemates using HPLC and SFC in a pharmaceutical discovery environment

✍ Scribed by Larry Miller; Matt Potter


Book ID
108160886
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
536 KB
Volume
875
Category
Article
ISSN
1873-376X

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## Abstract This article discusses the chromatographic resolution of a racemic pharmaceutical intermediate. Preparative batch high performance liquid chromatography (HPLC), supercritical fluid chromatography (SFC), steady‐state recycling (SSR), and simulated moving bed (SMB) were used to resolve a